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@#AIM: To compare the efficacy of invisible occlusion mirror and depressant membrane therapy in treatment of elderly amblyopia.<p>METHODS: Prospective study. Totally 112 cases(112 eyes)of monocular amblyopia aged 10-14 years were selected from June 2015 to December 2016 in our hospital. Among them, 55 cases(Group A)were treated with depressant membrane therapy and 57 cases(Group B)were treated with invisible concealer. The treatment compliance and efficacy of the two groups were evaluated, and the changes of corrected visual acuity before and after treatment were observed.<p>RESULTS: For 3, 6 and 12mo, there was no significant difference in treatment compliance between group A(98.2%, 96.4%, 92.7%)and group B(94.7%, 91.2%, 89.5%)(all <i>P</i>>0.05), but the effective rate of treatment(27.8%, 50.9%, 76.5%)was significantly lower than that of group B(46.3%, 71.2%, 92.2%), and the amblyopic corrected visual acuity of group B was better than that of group A(<i>P</i><0.05). After 12mo treatment, the total and actual cure rates of group A(52.7% and 56.9%)were significantly lower than those of group B(71.9% and 80.4%).<p>CONCLUSION: The treatment of monocular amblyopia over 10 years old with invisible occlusion mirror is superior to that of depressor membrane occlusion in improving visual acuity and curing rate.
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AIM:To investigate the effect of orthokeratology on stereopsis, accommodation parameters and ocular biological parameters in myopic patients. METHODS: The clinical data of 65 patients (130 eyes) with myopia in our hospital from January 2016 to May 2017 were analyzed and they were divided into high myopia group,moderate myopia group and slight myopia group. The changes of stereopsis, accommodation parameters and ocular biological parameters were compared between the myopic patients before and after the operation. RESULTS: The difference of distant vision, stereo acuity, accommodation range and accommodation sensitivity between the three groups were statistically significant (P<0.05). The uncorrected visual acuity, the degree of spherical equivalent and the diopter of cylindrical power in the myopic eyes were significantly lower than those before treatment,and the difference was statistically significant (P<0.05). The intraocular pressure and central corneal thickness were not different compared with before treatment (P>0. 05). After treatment, the corneal curvature was lower and axial length were higher than those before treatment, the difference was statistically significant (P<0.05). CONCLUSION: Orthokeratology can obviously improve the distance and near vision and stereoscopic vision function of myopic patients,which may slow the increase of axis and reduce the corneal curvature.
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Objective To study the clinical efficacy of bevacizumab in combination with chemotherapy in the treatment of advanced gastric cancer. Methods 60 cases of advanced gastric cancer patients as the research object (February 2016 to January 2017), (random draw, serial number and other treatment methods) 60 cases of advanced lung cancer patients were divided into two groups (experimental group and control group, 30caes). The control group received routine chemotherapy treatment, the experimental group on the basis of 75 mg / kg bevacizumab, two groups of patients treated for 42 days. Comparative analysis of two groups of patients with quality of life and short-term efficacy and other clinical indicators. Results The quality of life score of the control group was (60.30±9.20), significantly lower than that of the experimental group, and the score was (76.88±10.90) points, with statistical difference (P<0.05). In the experimental group, 3 cases were deteriorated, and 7 cases were stable. In the control group, 6 cases were worsened, and 12 cases were stable. Available experimental treatment group total effective number of cases to 20 cases, effective rate was 66.7%, the control group was 40.0%, two groups of patients with lung cancer during treatment there were no serious adverse reactions, the incidence rate of no significant difference. Conclusions The clinical curative effect of bevacizumab combined with chemical drugs in the treatment of advanced gastric cancer is ideal, high safety, can improve the quality of life of patients in a large extent, improve the clinical symptoms, has clinical significance.
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Objective To study the clinical efficacy of bevacizumab in combination with chemotherapy in the treatment of advanced gastric cancer. Methods 60 cases of advanced gastric cancer patients as the research object (February 2016 to January 2017), (random draw, serial number and other treatment methods) 60 cases of advanced lung cancer patients were divided into two groups (experimental group and control group, 30caes). The control group received routine chemotherapy treatment, the experimental group on the basis of 75 mg / kg bevacizumab, two groups of patients treated for 42 days. Comparative analysis of two groups of patients with quality of life and short-term efficacy and other clinical indicators. Results The quality of life score of the control group was (60.30±9.20), significantly lower than that of the experimental group, and the score was (76.88±10.90) points, with statistical difference (P<0.05). In the experimental group, 3 cases were deteriorated, and 7 cases were stable. In the control group, 6 cases were worsened, and 12 cases were stable. Available experimental treatment group total effective number of cases to 20 cases, effective rate was 66.7%, the control group was 40.0%, two groups of patients with lung cancer during treatment there were no serious adverse reactions, the incidence rate of no significant difference. Conclusions The clinical curative effect of bevacizumab combined with chemical drugs in the treatment of advanced gastric cancer is ideal, high safety, can improve the quality of life of patients in a large extent, improve the clinical symptoms, has clinical significance.